Abstract: Laparoscopic vagal sparing esophagogastrectomy for the treatment of early esophageal cancer has the advantages of minimal invasion, functional sparing and better quality of life, and it can radically resect the tumor. The clinical data of 3 patients in the Daping Hospital of Third Military Medical University and 9 patients in the Xijing Hospital of Digestive Diseases who received laparoscopic vagal sparing esophagogastrectomy from September 2009 to August 2013 were retrospectively analyzed. All the 12 patients were followed up for 1 24 months. One patient was complicated with transit hoarseness and 1 with cervical anastomotic fistular, and they were cured by conservative treatment; 1 patient was complicated with cervical anastomotic stricture, and was cured by dilatation for 3 times; no dysphagia and recurrence was observed in the other 9 patients during the follow up. Laparoscopic vagal sparing esophagogastrectomy is a good option for early esophageal cancer and benign esophageal diseases.